Scientific Literature



Synopsis: An implant-supported restoration of the maxillary anterior segment that is biologically, functionally, and esthetically acceptable following traumatic injuries in the maxillary anterior segment is always complex. Healing of the tissues is always difficult to control and the development of new techniques and materials to improve these treatments is still necessary.


The use of platelet concentrates is an interesting approach. The objective of this technique is to gather platelet growth factors and to inject them on a surgical site to stimulate the healing process. Leukocyte and platelet-rich fibrin (L-PRF) allows for the preparation of strong fibrin membranes that are enriched with cells (activated platelets, leukocytes, circulating cells) and platelet growth factors.


This autologous healing biomaterial is free of additives such as anticoagulants during blood harvesting or chemicals for activation. In addition, it is simple, inexpensive, and quick to prepare (15 minutes for all steps). The technique that is presented is specifically adapted to the practical needs in daily implant dentistry.


This case letter documents the use of L-PRF during the replacement of a fractured central incisor with an immediate post-extraction implant and crown placement. As a strong solid fibrin membrane, L-PRF is seen to be particularly easy to use in implant dentistry and periodontology. In addition, it offers a protective effect (both mechanical and biological) to the grafted area.


The Use of Leukocyte- and Platelet-Rich Fibrin During Immediate Postextractive Implantation and Loading for the Esthetic Replacement of a Fractured Maxillary

Central Incisor



J Oral Implantol 2012; 2012 Apr; 38(2):181-187. PubMed PMID: 22568469.


Medicine: 11

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