Scientific Literature



It is well established that, for several weeks following implant placement, the bone to implant bond is weaker as a result of the catabolic phase of bone. Strategies ranging from roughening the implant surface to applying osteoinductive materials have been employed in an attempt to re-engineer the bone response. A study was proposed to compare three different surface treatments. Implants of similar architecture from three manufacturers were evaluated to test early bone bonding.


Tested were 36 endosseous implants with variations in surface treatment from three different manufacturers (12 of each type). One implant of each design was placed in each of 6 animals (beagle dogs), 3 per side in the mandible. The same protocol was used in the contralateral side two weeks later following the same distribution of the previous implant placement procedure. The animals were sacrificed 3 weeks after the initial implant surgery.


For biomechanical testing, the bone blocks with implants were adapted to an electronic torque machine equipped with a 200 Ncm torque load cell. The implants were torque to interfacial fracture at a rate of ~ 0.19618 radians/sec, and the maximum torque value was recorded for each specimen. When compared to an acid-etched and particulate calcium phosphate coating (Nanotite? – Group 1) and a TiO blasted + HF etched surface (Osseospeed? – Group 2), at one week the Ossean? surface implants (acid etched and calcium phosphate impregnated – Group 3) had a 500% greater bone-bonding shear strength as demonstrated in a reverse torque pullout study.


The conclusion reached is that there is a limitation of biologic activity on purely etched surfaces and there is also a qualitative difference in some nanotextured + calcium phosphate impregnated surfaces. The Ossean? surface appears to be biologically active in the sense that bone goes directly to the anabolic phase without intervening bone breakdown. This is relevant in immediate load cases and for extraction site defects where the percentage of initial bone-to-implant contact is compromised.

Comparative Analysis of Early Bone Bonding Using Various Surface Treatments



2010, Academy of Osseointegration, Annual Meeting, P202


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